The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs
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چکیده
منابع مشابه
The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs
Atg9 is a multispanning transmembrane protein that is required for autophagosome formation. During autophagy, vesicles containing Atg9 are generated through an unknown mechanism and delivered to the autophagosome formation sites. We have previously reported that Atg9-containing membranes undergo continuous tubulation and fission during nutrient starvation in a manner dependent on the curvature-...
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The eucaryotic cell is organized in several compartments named organelles. These organelles and the cell itself are delimited by lipid membranes. The ssion of these membranes is required for the vesicular tra c between organelles. Endocytosis is the mechanism of vesicular tra c from the plasma membrane towards other organelles inside the cell. Dynamin is a guanosine triphosphatase implicated in...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2016
ISSN: 1949-2553
DOI: 10.18632/oncotarget.8028